Dr. Mary-Claire King (covered here previously) has a hell of a story to tell about the lead-up to the discovery of the “breast cancer gene”:
The week of April Fools’ Day of 1981 began badly. That Sunday night my husband told me he was leaving me. He had fallen in love with one of his graduate students, and they were headed back to the tropics the next day.
I was completely devastated. It was totally unexpected. 33 years later, I still don’t know what to say about it. I was just beside myself.
He gave me a new vacuum cleaner to soften the blow.
Go read it — her story is incredible.