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This Native American clan mother brought together 5 tribes under the Haudenosaunee Confederacy - and helped make the document that inspired the United States Constitution.
This Polish nurse sacrificed her safety, her marriage, her very family to save 2500 Jewish children from the Warsaw Ghetto during the Holocaust.
When her rebel husband was imprisoned, she continued the movement - by holding a castle under siege for three long, lonely years.
The only female emperor of China in history, her ruthless rise to power makes Game of Thrones look like a day at the beach.
To ensnare the scheming ministers who were ruining her life, this princess used guile, cunning, and a sophisticated knowledge of civil engineering.
When she was told to "go do women's work" after upstaging the medical community in her treatment of Hodgkin's disease, Dr. Vera Peters revolutionized breast cancer treatment through years of painstaking, meticulous work.
After being saved from demonic forces, this legendary Indian princess is then subjected to endless purity tests by her own husband. She eventually puts an end to his questions in a manner that surprised everyone.
One of the most famous women in American history, this hyper-capable Shoshone woman walked across America with a baby strapped to her back, in order to map it.
This superhero of early Iranian mythology starred in her own stories, and plenty of them.
Sor Juana Inés de La Cruz
This brilliant poet rose from illegitimacy and poverty to become one of the luminaries of her age - until she flew too close to the sun.