Ali Stroker became the first person in a wheelchair to perform on Broadway after her debut as Anna in "Spring Awakening."
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This pope was largely assumed to be male until she gave birth in the midst of a procession - and largely assumed to be factual until the 13th century.
Viking princess who decided she'd rather be a pirate than get married.
When her husband became deathly ill, this pregnant teen took the reins to become America's first female boat commander - all while fighting off a mutiny and keeping her husband alive.
This self-described "undutiful daughter" posed as a man to become the world's first female shipwright.
Isabel Godin des Odonais
To reunite with her husband, she went on a months-long trek through the jungle -- and was the only survivor.
Ida Laura Pfeiffer
Starting her travels at 45 years old, this globetrotter became a worldwide sensation for going boldly where no woman had gone before.
Marsha P. Johnson
This cheery godmother of trans civil rights masked a dark past of abuse.
Annie Jump Cannon
This astronomer threw off all the social conventions of her day to pursue her one true calling: the stars.
The illegitimate daughter of a minor noble, after losing her husband, she became one of the most powerful and fierce women in Italy - commanding troops, insulting Machiavelli, and fighting Cesare Borgia with unmatched ferocity.
When horse-riding Spaniards invaded, she defied her tribe to befriend one of the abandoned horses, using her new bond to fight off the Spanish.