The Colorado seventh-grader was unimpressed by the options her parents had to test water in their home. So she created a sensor-based device using chemically treated carbon nanotubes to do it faster.
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The illegitimate daughter of a minor noble, after losing her husband, she became one of the most powerful and fierce women in Italy - commanding troops, insulting Machiavelli, and fighting Cesare Borgia with unmatched ferocity.
Let her leprosy go untreated for years to make herself the perfect spy in the Japan-occupied Philippines - soldiers wouldn't touch her, so she could slip right through.
Roundly-despised and unfairly-maligned seductress of the bible who ran afoul of the wrong priests.
Possibly the most cartoonishly evil woman to have ever existed, this Merovingian queen was an endless source of assassination attempts - including, on one memorable occasion, her own young daughter.
The "Last of the Aboriginal Tasmanians" (she wasn't) used brains, brawn, and sheer will to carve a place for herself, even as the world was collapsing around her.
Through years of unrelenting protest, this Nigerian teacher felled a king, won women the right to vote, and taught all of Africa how to protest.
The poster child for childhood abuse, nobody should ever make a kids' movie about her.