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When horse-riding Spaniards invaded, she defied her tribe to befriend one of the abandoned horses, using her new bond to fight off the Spanish.
One of the greatest pharaohs to ever live, she built up Egypt so much that a generations-long sustained effort to erase her from history couldn't do the trick.
Olga of Kiev
Brutal princess-turned-Christian saint who burnt down enemy towns using pigeons.
Possibly the most cartoonishly evil woman to have ever existed, this Merovingian queen was an endless source of assassination attempts - including, on one memorable occasion, her own young daughter.
Isabella of France
After years of neglect and abuse from her husband, this queen raised an army and took over England for herself.
When she was told to "go do women's work" after upstaging the medical community in her treatment of Hodgkin's disease, Dr. Vera Peters revolutionized breast cancer treatment through years of painstaking, meticulous work.
When the English laid siege to her castle home, this Scottish woman bedeviled them until they gave up.
In 1931, a seventeen-year-old girl struck out Babe Ruth and Lou Gehrig in front of a crowd of thousands -- and then was benched into obscurity.
Escaped slave turned slave rescuer turned plantation-torching Union spymaster, she was part Moses, part Joan of Arc, part Spider-Man.
The first female mathematician in recorded history, and one of the luminaries of the ancient world - but her grisly death at the hands of a mob was only the start of her troubles.